abstract: in a wide search program towards new and efficient antimicrobial agents, a series of 4-substituted-1,2,4-triazolidine-3,5-dione derivatives namely urazoles holding an alkyl moiety at position 4 have been synthesized and tested for their in vitro antibacterial and antifungal activities. the structures of these compounds have been investigated by spectral data. the synthesized compounds...

starting from readily available 2-substituted-4-methylthiazole-5-carboxylic acid hydrazide (1), the title compounds were prepared. the reaction of compound 1 (r=ch3) with formic acid yielded 1-(formyl)-2-(2,4-dimethylthiazole-5-carboxyl) hydrazine (2). refluxing the latter with phosphorous pentasulfide in xylene afforded compound 3, the reaction of compound 2 with phosphorous pentoxide afforded...

three native turkish medicinal and aromatic plants (artemisia absinthum, artemisia santonicum and saponaria officinalis) were investigated to analyze their antioxidant activity, total phenolic content and antimicrobial activity. their total antioxidant activity was determined by using a β-carotene bleaching assay and their antimicrobial activity was determined by utilizing an agar disc diffusio...

nano dithiocarbamate (dtc) complex have been prepared by reaction between dithiocarbamate and metal salt under ultrasound irradiation. reaction conditions such as the ligand dtc and phennantroline concentration, aging time and the ultrasonic device power show important roles in the size, morphology and growth process of the final products. the dithiocarbamate complex nanoparticles have been pre...

wide range of quinazolinone biological properties including: antibacterial, anticancer, and anti-inflammatory activities encouraged us to synthesis some fused quinazolinone derivatives. anthranilic acid was condensed with chloro acylchloride followed by dehydration to form the benzoxazinone intermediate; subsequent addition of an amine provided the fused quinazolinones. deoxyvasicinone which wa...

objectives: the objective of this study was to analyze the fatty acid content, antioxidant, and antibacterial activities of hydro-methanolic extract of adonis wolgensis l. (a. wolgensis l.) growing wild in north of iran. materials and methods: oils of a. wolgensis l. was obtained by means of soxhlet apparatus from leaves and stems. methyl esters were derived from the oily mixtures by trans-este...

substituted 1, 2, 4- triazoles have shown multiple biological activities such as anti-inflammatory, anti fungal, etc. 5-mercapto triazoles were prepared from the potassium dithiocarbazinates. these triazoles were used for preparation of different derivatives by two different schemes. in the first scheme the mannich bases were prepared from 5- marcapto-s triazole quinazolines. the 5-marcato-s-tr...

fractions obtained from partitioning of aerial methanolic extract of euphorbia aellenii with chloroform (e2), ethyl acetate (e3), n-butanol (e4) and water (e5) were investigated in vitro for their phytotoxicity, insecticidal, anti-leishmanial, cytotoxicity, antibacterial and antifungal activities. sample e2 appeared to have significant phytotoxic activity. in the insecticidal screening study on...

antibacterial activity of the aerial extracts from xanthium brasilicum prepared in methanol, diethyl ether, petroleum benzene and an equal mixture of the three solvents were studied against bacterial laboratory standards and clinical isolates using the disk diffusion method. the best antibacterial results were obtained when methanol or the solvent mixture was used. the crude extract with the hi...

background drug resistance of microorganisms to antimicrobial agents is on the rise. therefore, an alternative route to overcome drug resistance of various microorganisms is needed. objectives this study was conducted to assess antibacterial activity of silver nanoparticles (agnps) produced by satureja hortensis extract against bacillus cereus isolated from soil of sistan plain (zabol, southeas...